Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Chronic hepatitis and liver cirrhosis lead to accumulation of genetic alterations driving HCC pathogenesis. This study is designed to explore genomic landscape of HCC in Egyptian patients by whole exome sequencing. Methods: Whole exome sequencing using Ion Torrent was done on 13 HCC patients, who underwent surgical intervention (7 patients underwent living donor liver transplantation (LDLT) and 6 patients had surgical resection}. Results: Mutational signature was mostly S1, S5, S6, and S12 in HCC. Analysis of

Capturing the diverse microbiota from healthy and/or stress resilient plants for further preservation and transfer to unproductive and pathogen overloaded soils, might be a tool to restore disturbed plant-microbe interactions. Here, we introduce Aswan Pink Clay as a low-cost technology for capturing and storing the living root microbiota. Clay chips were incorporated into the growth milieu of barley plants and developed under gnotobiotic conditions, to capture and host the rhizospheric microbiota. Afterward, it was tested by both a culture-independent (16S rRNA gene metabarcoding) and

People with visual impairments often have difficulty locating misplaced objects. This can be a major barrier to their independence and quality of life. Retinal prostheses can restore some vision to people with severe vision loss. We introduce a novel real-time system for locating any misplaced objects for people with visual impairments using retinal prostheses. The system combines One For All (OFA) for Visual Grounding and Google Speech Recognition to identify the object to be located. It then uses an image processing technique called grabCut to extract the object from the background to

Nuclei detection and segmentation in histopathological images is a prerequisite step for quantitative analysis including morphological shape and size to help in identifying cancer prognosis. Digital pathology field aims to improve the quality of cancer diagnosis and has helped pathologists to reduce their efforts and time. Different deep learning architectures are widely used recently in Digital pathology field, yielding promising results in different problems. However, Deep convolutional neural networks (CNNs) need a large subset of labelled data that are not easily available all the time in

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and poses a major burden on the human health worldwide. At the moment, treatment of CRC consists of surgery in combination with (neo)adjuvant chemotherapy and/or radiotherapy. More recently, immune checkpoint blockers (ICBs) have also been approved for CRC treatment. In addition, recent studies have shown that radiotherapy and ICBs act synergistically, with radiotherapy stimulating the immune system that is activated by ICBs. However, both treatments are also associated with severe toxicity and efficacy issues, which can

Document forgery detection is becoming increasingly important in the current era, as forgery techniques are available to even inexperienced users. Source printer identification is a method for identifying the source printer and classifying the questioned document into one of the printer classes. According to what we know, most earlier studies segmented documents into characters, words, and patches or cropped them to obtain large datasets. In contrast, in this paper, we worked with the document as a whole and a small dataset. This paper uses three techniques dependent on CNN to find the

Rice is considered a strategic crop in Egypt as it is regularly consumed in the Egyptian people’s diet. Even though Egypt is the highest rice producer in Africa with a share of 6 million tons per year [5], it still imports rice to satisfy its local needs due to production loss, especially due to rice disease. Rice blast disease is responsible for 30% loss in rice production worldwide [9]. Therefore, it is crucial to target limiting yield damage by detecting rice crops diseases in its early stages. This paper introduces a public multispectral and RGB images dataset and a deep learning pipeline

The amount and variety of raw data generated in the agriculture sector from numerous sources, including soil sensors and local weather stations, are proliferating. However, these raw data in themselves are meaningless and isolated and, therefore, may offer little value to the farmer. Data usefulness is determined by its context and meaning and by how it is interoperable with data from other sources. Semantic web technology can provide context and meaning to data and its aggregation by providing standard data interchange formats and description languages. In this paper, we introduce the design

Secret Image Sharing (SIS) transfers an image to mutually suspicious receivers as n meaningless shares, where k or more shares must be present to recover the secret. This paper proposes a (k, n)-SIS system for any image type using polynomial interpolation based on Lagrange polynomials, where the generated shares are of size 1/k of the secret image size. A full encryption system, consisting of substitution and permutation stages, is employed by using the generalized Tent map as a source of randomness. In addition to using a long and sensitive system key, steganography using the Least

Customer churn poses a formidable challenge within the Telecom industry, as it can result in significant revenue losses. In this research, we conducted an extensive study aimed at developing a viable customer churn prediction method. Our method utilizes the Apriori algorithm's strength to identify the key causes of customer churn. In the pursuit of this goal, we utilized multiple machine learning predictive models. All of which were developed from the insights gleaned from the Apriori algorithm's feature extraction for churning customers. This extensive analysis encompassed a spectrum of