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Coffee and multiple sclerosis (MS)
Multiple Sclerosis (MS) is a long-term autoimmune disorder affecting the central nervous system, marked by inflammation, demyelination, and neurodegeneration. While the exact cause of MS remains unknown, recent research indicates that environmental factors, particularly diet, may influence the disease's risk and progression. As a result, the potential neuroprotective effects of coffee, one of the most popular beverages worldwide, have garnered significant attention due to its rich content of bioactive compounds. This chapter explores the impact of coffee consumption on patients with Multiple
A Robust Deep Learning Detection Approach for Retinopathy of Prematurity
Retinal retinopathy of prematurity (ROP), an abnormal blood vessel formation, can occur in a baby who was born early or with a low birth weight. It is one of the primary causes of newborn blindness globally. Early detection of ROP is critical for slowing and stopping the progression of ROP-related vision impairment which leads to blindness. ROP is a relatively unknown condition, even among medical professionals. Due to this, the dataset for ROP is infrequently accessible and typically extremely unbalanced in terms of the ratio of negative to positive images and the ratio of each stage of it
Mobile Application Code Generation Approaches: A Survey
With the extensive usage of mobile applications in daily life, it has become crucial for the companies of software to develop applications for the most popular platforms such as Android and iOS in the shortest possible time and at the lowest possible cost. However, ensuring consistent UIs and functionalities among cross-platform versions can be challenging and costly since different platforms have their own UI controls and programming languages. Also, when cross-platform tools are used, it is always time consuming to learn a new language. Many solutions were proposed to achieve the native
Light-Weight Intelligent Egyptian Food Detector For Diabetes Management
Diabetic patients need a management tool that combines multiple features and tracks and views detailed data time-efficiently. Effective food logging is an important element of health monitoring. In this paper, we propose 'Suger.ly', a lightweight mobile application with artificial intelligence food recognition for diabetes management. The system has been trained to recognize 101 distinct types of food, with a focus on Egyptian cuisine. The app can then get nutritional value and insulin calculations. The results obtained from the Single-Shot multibox Detection (SSD) MobileNet-V1 food detection
Light-Weight Food Image Classification For Egyptian Cuisine
Food is an integral aspect of daily life in all cultures. It highly affects people's diets, eating behaviors, and overall health. People with poor eating habits are usually overweight or obese, which leads to chronic diseases such as diabetes and cardiovascular disease. Today, the classification of food images has several uses in managing medical conditions and dieting. Deep convolutional neural network (DCNN) architectures provide the foundation for the most recent food recognition models. However, DCNNs are computationally expensive due to high computation time and memory requirements. In
Blockchain Application on Big Data Security
In recent years, advances in technology in several industries have resulted in massive data collections on the web. It raises worries about large data security and protection. The advent of Blockchain technology has caused a revolution in the security field for different applications. The distributed ledger is stored on each Blockchain node, which enhances security and data transparency. On the Blockchain network, illegal users are not authorized to undertake any fault transactions. In this article, we will discuss how Blockchain may be employed to secure the big data. We explain the problems
Fully Automated Fabric Defect Detection Using Additive Wavelet Transform
This paper introduces a proposed fabric defect detection technique based on additive wavelet transform. In this paper, à trous wavelet is utilized to extract the approximate sub image at an appropriate level. The objective of the proposed technique is to enhance energy of defective region and attenuate energy of background in the selected level. An improved thresholding method based on statistical calculation is used. © 2020, Menoufia University, Faculty of Electronic Engineering. All rights reserved.
Bilingual Embeddings andWord Alignments for Translation Quality Estimation
This paper describes our submission UFAL MULTIVEC to the WMT16 Quality Estimation Shared Task, for English- German sentence-level post-editing effort prediction and ranking. Our approach exploits the power of bilingual distributed representations, word alignments and also manual post-edits to boost the performance of the baseline QuEst++ set of features. Our model outperforms the baseline, as well as the winning system in WMT15, Referential Translation Machines (RTM), in both scoring and ranking sub-tasks. © 2016 Association for Computational Linguistics.
The FDA-Approved Drug Cobicistat Synergizes with Remdesivir to Inhibit SARS-CoV-2 Replication in Vitro and Decreases Viral Titers and Disease Progression in Syrian Hamsters
Combinations of direct-acting antivirals are needed to minimize drug resistance mutations and stably suppress replication of RNA viruses. Currently, there are limited therapeutic options against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and testing of a number of drug regimens has led to conflicting results. Here, we show that cobicistat, which is an FDA-approved drug booster that blocks the activity of the drug-metabolizing proteins cytochrome P450-3As (CYP3As) and P-glycoprotein (P-gp), inhibits SARS-CoV-2 replication. Two independent cell-to-cell membrane fusion
Identifying Immunological and Clinical Predictors of COVID-19 Severity and Sequelae by Mathematical Modeling
Since its emergence as a pandemic in March 2020, coronavirus disease (COVID-19) outcome has been explored via several predictive models, using specific clinical or biochemical parameters. In the current study, we developed an integrative non-linear predictive model of COVID-19 outcome, using clinical, biochemical, immunological, and radiological data of patients with different disease severities. Initially, the immunological signature of the disease was investigated through transcriptomics analysis of nasopharyngeal swab samples of patients with different COVID-19 severity versus control
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